Health issues

DYSPLASIA


Hip Dysplasia (HD) afflicts millions of dogs each year and can result in debilitating orthopaedic disease of the hip. Many dogs will suffer from osteoarthritis, pain, and lameness, shortened work longevity, and reduced performance, costing owners and breeders a lot of money  in veterinary care.The occurrence of HD is well documented in the large and giant breed dogs. The Landseer is no exception.

Hip dysplasia was first described in 1937. It is a disease of complex inheritance. Accordingly, breed clubs and dog breeders have attempted to eliminate HD through selective breeding strategies. In general, the reduction of HD frequency in Landseer dogs has been disappointing in some countries, because several clubs and breeders did not follow the rules strict enough or find HD of no importance. Other clubs and their breeders get excellent results over long years.

Hereditary diseases are everywhere where living creatures reproduce themselves. The task of the breeder is to keep their appearance as small as possible or make them disappear. Only then can one speak of a responsible breeding.


CTP - THROMBOPATHIA

Thrombopathia is a disorder of small blood cells called platelets or thrombocytes. Platelets play an important role at several stages of the body's response to any injury that causes bleeding. One function of platelets is to aggregate or "clump" at the site of a blood vessel injury to form an initial plug. Platelets also facilitate blood clotting, in conjunction with the clotting factors, and release substances active in inflammation and tissue repair.

In Landseer thrombopathia, platelets do not respond normally to the activation signals that occur following injury to a blood vessel. Platelet aggregation does not occur. Dogs with this condition are therefore more susceptible to bruising and hemorrhage.

Thrombopathia is an autosomal recessive trait. Both parents must carry the abnormal gene for the offspring to be affected.

--"Landseer Thrombopathia" - Link

--"Calcium-Diacylglycerol Guanine Nucleotide Exchange Factor I gene mutations associated with loss of function in canine platelets" - Link

International Shipments Samples - Link