VIB-RUG Department of Molecular Biomedical Research
Molecular ImmunoBiotechnology Unit
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VIB-RUG Department of Molecular Biomedical Research Molecular ImmunoBiotechnology Unit
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Therapeutic
monoclonal antibodies used in clinical practice anno 2004.
(1) Induces T-cell anergy to prevent graft rejection after transplantation (2)
Binds
Integrin: prevents clothing by preventing platelet aggregation (during surgery),
angioplasty (3)
B-cell
lymphoma (NHL) marker: trigger kills lymphoma cell: first line medication (4)
Acute graft rejection after
renal transplantation (also liver) (5)
Acute graft rejection after
renal transplantation (also liver) (6)
RSV:
prevents infection in premature children (7)
Prevents inflammation (TH1)
in rheumatoid
arthritis (RA) and Crohn’s
disease. (8)
Carcinoma marker, kills
tumor cells: breast cancer treatment (9)
Relapsed
acute myeloid leukemia, antibody-targeted chemotherapy (ATC) (10)
Allogeneic transplant,
RA, lymphoma, leukemia,
vasculitis, multiple
sclerosis,
malignant T-cell purging (11)
Colorectal cancer marker (not signaling) (12) radioimmunotherapy treatment for non-Hodgkins lymphoma (13) Rheumatoid arthritis (14) Allergy (15) Colon cancer (16) anti angiogenesis in metastatic colon cancer
And more than 300 in clinical trails....
[Antibodies] [Immunotherapy] [BsAb] [Tribody]
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