|
Domain for targeting |
Derived from |
Platform Trade Name |
Company |
|
|
Antibody derived: |
scFv
|
Human antibody VH + VL domains |
SCA |
Micromet /
Enzon |
 |
|
Human VH or VL
|
Stable human V domains |
dAbs |
Domantis |
 |
|
Camel/Llama VHH
|
Camel or Llama heavy chain mAbs |
Nanobodies |
Ablynx |
 |
|
non-antibody derived: |
|
Ankyrin repeats
|
Synthetic human ankyrin repeats |
DARPins |
Molecular Partners |
 |
|
Fibronectin |
Trimeric human plasminogen binding protein |
Tetranectins |
Borean Pharma |
 |
|
Fibronectin |
10th fibronectin type III domain (human) |
AdNectins |
Compound
Therapeutics |
 |
|
Transferin |
Non-glycosylated form of human transferin |
Trans-bodies |
BioRexis |
|
|
Lipocalins |
Derived from P. brassicae butterly |
Anticallins |
Pieris Proteolab |
|
|
g-Crystallin |
Stable human protein from eye lens |
Affilins |
Scil
Proteins |
|
|
Cystein knots |
E. elaterium trypsin inhibitor II – cyclotide
EETI-II |
Microbodies |
Selecore |
|
|
Protein A domains |
S. aureus
protein A domain |
Affibodies |
Affibody |
 |
